SOAR Member Profiles

Emily Callison

• SOAR Position: SOAR President (2025-2026); URC Student Worker (2025-2026); READY to SOAR Coordinator (2024-2026); Peer Mentor Scholar (2024-2025); Member
• Major: Psychology; Pre-Med Emphasis
• Faculty Mentor(s): Dr. David Edward Nelson and Dr. Tiffany Rogers

Current Focus: Monitoring Macrophage Anti-Fungal Activity Using Live-Cell Imaging

Project Description

The Nelson Lab investigates macrophage-pathogen interactions, with a current focus on Cryptococcus neoformans. This facultative intracellular fungal pathogen enters the lungs via the inhalation of its airborne spores and has developed immune-evasion strategies that enable it to replicate within host cells, disseminate throughout the body, and ultimately cause life-threatening fungal meningitis in immunocompromised individuals. My research utilizes live-cell imaging to elucidate these evasion mechanisms, with the goal of advancing our understanding of fungal pathogenesis and improving treatments for vulnerable populations.

Why does this topic interest you?

Witnessing my sister’s battle with aplastic anemia exposed me to the profound complexities of the immune system. While her condition was autoimmune, this experience sparked a deep curiosity regarding how the body defends itself against disease and how those defenses can sometimes falter. I’m fascinated by the pivotal role macrophages play in immunity and pathogen defense. Studying macrophages and their interactions with pathogens aligns with my passion for translational medicine: understanding the science at a cellular level and imagining its potential applications in treating diseases and improving patient outcomes.

What are your professional aspirations?

I aspire to become a physician who is committed to advancing the field of medicine through impactful research, education and mentorship, and advocating for healthcare equity, particularly for individuals with intellectual and developmental disabilities. After receiving my bachelor’s degree from MTSU, I plan to attend medical school to receive a Doctorate of Medicine (M.D.).

Do you have any advice for future researchers?

Every great discovery begins with a spark of curiosity, a desire to bridge the gap between the known and unknown, and the mind of a dreamer. Though, I have found that on the path to discovery, the guidance and support of those who have walked the path before me are one of the greatest keys to success. As you embark on your research journey, remember that you are not alone. Don’t be afraid to seek support! There is no limit to what you can achieve with a bit of guidance and a whole lot of determination!

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